Car: 2006 Chrysler 300C
Join Date: Apr 2009
Location: DC Metro Area
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That's too much water lost. I'm thinking you got a big leak somewhere; either external or (say it ain't so) internal. Obviously refill that radiator, but check your oil dipstick to make certain the oil isn't frothy/foamy. That's bad news if it is; it means you have an internal leak, probably a blown head gasket, allowing your coolant to mix with the oil. Let's hope, if it is a leak, that it's external, such as a hose or even the radiator itself. These suggestions are old-school for older cars, so I imagine someone more familiar with the newer car tech could chime in and give more (accurate) info.
As for me and my '06 C3C, the dealer does all of my maintenance and the always check/top off my fluids. The last temperature problem I had was my A/C dying on me. Dealer thought it was the A/C motor, but it turned out one of the (plastic) fans cracked causing it to scrape against the shroud, making the car think it was the motor that was going bad. Amazingly, despite the cracked fan, the mechanic was surprised the car never overheated, the temp gage remaining at the slightly-below halfway mark. This makes me believe the 5.7 Hemis are very good at temperature management. The loss of water from your system indicates something is seriously amiss. Let's hope it's a simple, but external leak.